Not sure what version of CUDA you’re running, but I had the same “Torch not compiled with CUDA enabled” issue when I installed both ComfyUI 0.8.24 and 0.8.25 while running CUDA 13.1.
I opened a command prompt (run as administrator), navigated to the ComfyUI scripts directory (C:\Users\…\Documents\ComfyUI\.venv\Scripts), and then entered the following:
pip3 uninstall torch torchvision torchaudio
After that’s done, reinstall using:
pip3 install torch torchvision torchaudio --index-url https://download.pytorch.org/whl/cu130
(note that there’s not currently a pytorch cu131, but cu130 seems to be working for me, and ComfyUI is now working)