# MacStudio Sequoia 15.1 cannot open comfyui 0.4.19

**URL:** <https://forum.comfy.org/t/macstudio-sequoia-15-1-cannot-open-comfyui-0-4-19/1590>\
**Category:** Mac\
**Tags:** issue, starting-comfyui\
**Created:** [February 19, 2025, 7:53am UTC](https://forum.comfy.org/t/macstudio-sequoia-15-1-cannot-open-comfyui-0-4-19/1590 "2025-02-19T07:53:12Z")\
**Posts on this page:** 10\
**Page:** 1

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**Author:** ![yuzibiubiu](https://avatars.discourse-cdn.com/v4/letter/y/edb3f5/32.png) [@yuzibiubiu](https://forum.comfy.org/u/yuzibiubiu)\
**Post date:** [February 19, 2025, 7:53am UTC](https://forum.comfy.org/t/macstudio-sequoia-15-1-cannot-open-comfyui-0-4-19/1590/1 "2025-02-19T07:53:12Z")

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![37f3c73059ce8c15269ced3bb6c136e5](https://canada1.discourse-cdn.com/flex009/uploads/comfyui1/original/1X/26c0f99e1c5baada4ec3adfae31debb1c8901dc6.png)

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**Author:** ![yuzibiubiu](https://avatars.discourse-cdn.com/v4/letter/y/edb3f5/32.png) [@yuzibiubiu](https://forum.comfy.org/u/yuzibiubiu)\
**Post date:** [February 19, 2025, 7:56am UTC](https://forum.comfy.org/t/macstudio-sequoia-15-1-cannot-open-comfyui-0-4-19/1590/2 "2025-02-19T07:56:11Z")

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My logs have been uploaded successfully.

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**Author:** ![filtered](https://yyz1.discourse-cdn.com/flex009/user_avatar/forum.comfy.org/filtered/32/149_2.png) [@filtered](https://forum.comfy.org/u/filtered)\
**Post date:** [February 19, 2025, 9:00am UTC](https://forum.comfy.org/t/macstudio-sequoia-15-1-cannot-open-comfyui-0-4-19/1590/3 "2025-02-19T09:00:44Z")

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Thanks @yuzibiubiu - can see the issue. A network timeout when downloading one of the packages.

```auto
[2025-02-19 15:21:29.001] [info] x Failed to download `spandrel==0.4.1`
  |-> Failed to write to the distribution cache
  `-> Failed to download distribution due to network timeout. Try increasing
      UV_HTTP_TIMEOUT (current value: 30s).

```

The fastest way to fix this is to delete the `.venv` directory in the location where you installed ComfyUI. The default location is:

```auto
~/Documents/ComfyUI/.venv

```

The python packages you have already downloaded are cached by `uv` - you will not need to download them again. But just in case, you can simply rename the folder instead of deleting it.

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<div class="post-metadata">

**Author:** ![yuzibiubiu](https://avatars.discourse-cdn.com/v4/letter/y/edb3f5/32.png) [@yuzibiubiu](https://forum.comfy.org/u/yuzibiubiu)\
**Post date:** [February 19, 2025, 9:05am UTC](https://forum.comfy.org/t/macstudio-sequoia-15-1-cannot-open-comfyui-0-4-19/1590/4 "2025-02-19T09:05:58Z")

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Thanks,I will try.

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**Author:** ![yuzibiubiu](https://avatars.discourse-cdn.com/v4/letter/y/edb3f5/32.png) [@yuzibiubiu](https://forum.comfy.org/u/yuzibiubiu)\
**Post date:** [February 19, 2025, 9:30am UTC](https://forum.comfy.org/t/macstudio-sequoia-15-1-cannot-open-comfyui-0-4-19/1590/5 "2025-02-19T09:30:12Z")

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x Failed to create virtualenv  
`-> The directory `.venv`exists, but it's not a virtual environment yuzibiubiudeMac-Studio% echo "_-end-1739956704659:$?" _-end-1739956704659:1 /Applications/ComfyUI.app/Contents/Resources/uv/macos/uv "pip" "install" "--pre" "torch" "torchvision" "torchaudio" "--index-url" "https://download.pytorch.org/whl/nightly/cpu" echo "_-end-1739957038321:$?" yuzibiubiudeMac-Studio% /Applications/ComfyUI.app/Contents/Resources/uv/macos/uv "pip" "install" "--pre" "torch" "torchvision" "torchaudio" "--index-url" "https ://download.pytorch.org/whl/nightly/cpu" error: Failed to inspect Python interpreter from active virtual environment at`.venv/bin/python3` Caused by: Python interpreter not found at`/Users/yuzibiubiu/Documents/ComfyUI/.venv/bin/python3`  
yuzibiubiudeMac-Studio% echo “\_-end-1739957038321:$?”  
_-end-1739957038321:2  
/Applications/ComfyUI.app/Contents/Resources/uv/macos/uv “venv” “–python” “3.12” “–python-preference” “only-managed”  
echo "_-end-1739957038580:$?"  
yuzibiubiudeMac-Studio% /Applications/ComfyUI.app/Contents/Resources/uv/macos/uv  
“venv” “–python” “3.12” “–python-preference” “only-managed”  
Using CPython 3.12.8  
Creating virtual environment at: .venv  
uv::venv::creation

x Failed to create virtualenv  
`-> The directory `.venv` exists, but it’s not a virtual environment  
yuzibiubiudeMac-Studio% echo “\_-end-1739957038580:$?”  
\_-end-1739957038580:1

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<div class="post-metadata">

**Author:** ![filtered](https://yyz1.discourse-cdn.com/flex009/user_avatar/forum.comfy.org/filtered/32/149_2.png) [@filtered](https://forum.comfy.org/u/filtered)\
**Post date:** [February 19, 2025, 9:34am UTC](https://forum.comfy.org/t/macstudio-sequoia-15-1-cannot-open-comfyui-0-4-19/1590/6 "2025-02-19T09:34:20Z")

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> [@yuzibiubiu](#):
>
> `The directory `.venv`exists`

Are you certain you removed it? Can you please go into a bit more detail on the steps taken?

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**Author:** ![yuzibiubiu](https://avatars.discourse-cdn.com/v4/letter/y/edb3f5/32.png) [@yuzibiubiu](https://forum.comfy.org/u/yuzibiubiu)\
**Post date:** [February 19, 2025, 9:36am UTC](https://forum.comfy.org/t/macstudio-sequoia-15-1-cannot-open-comfyui-0-4-19/1590/7 "2025-02-19T09:36:51Z")

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![image](https://canada1.discourse-cdn.com/flex009/uploads/comfyui1/original/1X/8b1f3f009fe7838c5acb8c09822e73e05baa61b7.png)  
I deleted all the files in this folder. Then, when I reopened it, it prompted me to re-download.‘Python packages that are required to run ComfyUI are not installed.’

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<div class="post-metadata">

**Author:** ![filtered](https://yyz1.discourse-cdn.com/flex009/user_avatar/forum.comfy.org/filtered/32/149_2.png) [@filtered](https://forum.comfy.org/u/filtered)\
**Post date:** [February 19, 2025, 8:32pm UTC](https://forum.comfy.org/t/macstudio-sequoia-15-1-cannot-open-comfyui-0-4-19/1590/8 "2025-02-19T20:32:53Z")

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Ah, thank you. Can you please remove the folder itself?

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<div class="post-metadata">

**Author:** ![yuzibiubiu](https://avatars.discourse-cdn.com/v4/letter/y/edb3f5/32.png) [@yuzibiubiu](https://forum.comfy.org/u/yuzibiubiu)\
**Post date:** [February 20, 2025, 2:22am UTC](https://forum.comfy.org/t/macstudio-sequoia-15-1-cannot-open-comfyui-0-4-19/1590/9 "2025-02-20T02:22:47Z")

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thanks, it can be used now.

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<div class="post-metadata">

**Author:** ![rhuang](https://yyz1.discourse-cdn.com/flex009/user_avatar/forum.comfy.org/rhuang/32/21_2.png) [@rhuang](https://forum.comfy.org/u/rhuang)\
**Post date:** [February 20, 2025, 7:37pm UTC](https://forum.comfy.org/t/macstudio-sequoia-15-1-cannot-open-comfyui-0-4-19/1590/10 "2025-02-20T19:37:17Z")

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