I wanted to add I have the same issue. But I captured the comfyui.log and post it below so everyone can see it. Basically, I think that if you already have a Python installation on your computer above 3.12, there is no way to install or use ComfyUI. But, as you can see from this log, there are a lot of other issues. I have an AMD laptiop, and its wanting to load NVIDIA only files!
[2026-03-15 10:57:55.725] [info] comfy-aimdo failed to load: Could not find module ‘C:\Users\Ryzen9\Downloads\ComfyUI.venv\Lib\site-packages\comfy_aimdo\aimdo.dll’ (or one of its dependencies). Try using the full path with constructor syntax.
NOTE: comfy-aimdo is currently only support for Nvidia GPUs
[2026-03-15 10:57:55.845] [info] Adding extra search path custom_nodes C:\Users\Ryzen9\Downloads\ComfyUI\custom_nodes
Adding extra search path download_model_base C:\Users\Ryzen9\Downloads\ComfyUI\models
Adding extra search path custom_nodes C:\Users\Ryzen9\AppData\Local\Programs\ComfyUI\resources\ComfyUI\custom_nodes
[2026-03-15 10:57:55.846] [info] Setting output directory to: C:\Users\Ryzen9\Downloads\ComfyUI\output
Setting input directory to: C:\Users\Ryzen9\Downloads\ComfyUI\input
Setting user directory to: C:\Users\Ryzen9\Downloads\ComfyUI\user
[2026-03-15 10:57:56.788] [info] [START] Security scan
[DONE] Security scan
** ComfyUI startup time: 2026-03-15 10:57:56.775
[2026-03-15 10:57:56.790] [info] ** Platform: Windows
** Python version: 3.12.11 (main, Aug 18 2025, 19:17:54) [MSC v.1944 64 bit (AMD64)]
** Python executable: C:\Users\Ryzen9\Downloads\ComfyUI.venv\Scripts\python.exe
** ComfyUI Path: C:\Users\Ryzen9\AppData\Local\Programs\ComfyUI\resources\ComfyUI
** ComfyUI Base Folder Path: C:\Users\Ryzen9\AppData\Local\Programs\ComfyUI\resources\ComfyUI
** User directory: C:\Users\Ryzen9\Downloads\ComfyUI\user
** ComfyUI-Manager config path: C:\Users\Ryzen9\Downloads\ComfyUI\user__manager\config.ini
** Log path: C:\Users\Ryzen9\Downloads\ComfyUI\user\comfyui.log
[2026-03-15 10:57:57.476] [info] [ComfyUI-Manager] Skipped fixing the ‘comfyui-frontend-package’ dependency because the ComfyUI is outdated.
[2026-03-15 10:57:57.478] [info] [PRE] ComfyUI-Manager
[2026-03-15 10:57:58.924] [error] Windows fatal exception: access violation
Stack (most recent call first):
File “C:\Users\Ryzen9\Downloads\ComfyUI.venv\Lib\site-packages\torch\cuda_init_.py”, line 182 in is_available
File “C:\Users\Ryzen9\Downloads\ComfyUI.venv\Lib\site-packages\comfy_kitchen\backends\cuda_init_.py”, line 639 in register
File "C:\Users\Ryzen9\Downloads\ComfyUI.venv\Lib\site-packages\comfy_kitchen\backends\cuda_init.py", line 650 in
File “”, line 488 in _call_with_frames_removed
File “”, line 999 in exec_module
File “”, line 935 in _load_unlocked
File “”, line 1331 in _find_and_load_unlocked
File “”, line 1360 in _find_and_load
File “”, line 488 in _call_with_frames_removed
File “”, line 1415 in handle_fromlist
File "C:\Users\Ryzen9\Downloads\ComfyUI.venv\Lib\site-packages\comfy_kitchen_init.py", line 3 in
File “”, line 488 in _call_with_frames_removed
File “”, line 999 in exec_module
File “”, line 935 in _load_unlocked
File “”, line 1331 in _find_and_load_unlocked
File “”, line 1360 in _find_and_load
File “C:\Users\Ryzen9\AppData\Local\Programs\ComfyUI\resources\ComfyUI\comfy\quant_ops.py”, line 5 in
File “”, line 488 in _call_with_frames_removed
File “”, line 999 in exec_module
File “”, line 935 in _load_unlocked
File “”, line 1331 in _find_and_load_unlocked
File “”, line 1360 in _find_and_load
File “C:\Users\Ryzen9\AppData\Local\Programs\ComfyUI\resources\ComfyUI\comfy\memory_management.py”, line 5 in
File “”, line 488 in _call_with_frames_removed
File “”, line 999 in exec_module
File “”, line 935 in _load_unlocked
File “”, line 1331 in _find_and_load_unlocked
File “”, line 1360 in _find_and_load
File “C:\Users\Ryzen9\AppData\Local\Programs\ComfyUI\resources\ComfyUI\comfy\utils.py”, line 23 in
File “”, line 488 in _call_with_frames_removed
File “”, line 999 in exec_module
File “”, line 935 in _load_unlocked
File “”, line 1331 in _find_and_load_unlocked
File “”, line 1360 in _find_and_load
File “C:\Users\Ryzen9\AppData\Local\Programs\ComfyUI\resources\ComfyUI\main.py”, line 194 in